RANGAP1 (N-term), 20-49 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RANGAP1 (N-term), 20-49 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.45 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1. RanGAP1, is a homodimeric 65-kD polypeptide thatspecifically induces the GTPase activity of RAN, but not of RAS byover 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, aregulator molecule that keeps RAN in the active, GTP-bound state.The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequenceis unrelated to that of GTPase activators for other RAS-relatedproteins, but is 88% identical to Fug1, the murine homolog of yeastRna1p. RanGAP1 and RCC1 control RAN-dependent transport between thenucleus and cytoplasm. RanGAP1 is a key reg |
| Immunogen | n/a |
| Other Names | [Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD] |
| Gene, Accession # | [RANGAP1], Gene ID: 5905, NCBI: NP_001265580.1, UniProt: P46060 |
| Catalog # | MBS9213438 |
| Price | $165, $370 |
| Order / More Info | RANGAP1 (N-term), 20-49 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang, J., et al. Biochem. Biophys. Res. Commun. 375(2):252-255(2008) Zuccolo, M., et al. EMBO J. 26(7):1853-1864(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Vertegaal, A.C., et al. Mol. Cell Proteomics 5(12):2298-2310(2006) Vertegaal, A.C., et al. Mol. Cell Proteomics 5(12):2298-2310(2006) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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