AKT1S1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT1S1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: AKT1S1 antibody is human, mouse and rat reactive. At least three isoforms of AKT1S1 are known to exist. AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia (1). AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy (2). Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S
ImmunogenImmunogen: AKT1S1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1. Buffer: AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[AKT1S1; Lobe; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate; AKT1 substrate 1 (proline-rich)], [AKT1S1; AKT1S1; Lobe; PRAS40]
Gene, Accession #[AKT1S1], Gene ID: 84335, NCBI: NP_115751, UniProt: Q96B36
Catalog #MBS153593
Price$375
Order / More InfoAKT1S1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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