Edit |   |
---|---|
Antigenic Specificity | CD276 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.8mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CD276 protein. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found |
Immunogen | Immunogen: Synthetic peptide corresponding to residues near the C terminal of human CD276 Immunogen Type: Peptide |
Other Names | [B7H3; B7-H3; B7RP-2; 4Ig-B7-H3] |
Gene, Accession # | [CD276], Gene ID: 80381, NCBI: NP_001019907, UniProt: Q5ZPR3 |
Catalog # | MBS9429581 |
Price | $255 |
Order / More Info | CD276 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |