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Antigenic Specificity | Polymyxin B (PMB) |
Clone | [45] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | unconjugated |
Size | 0.2 mg |
Concentration | n/a |
Applications | Immunoassay (IA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal antibody 45 reacts with Polymyxin B. The antibody binds to free Polymyxin B as well as to Polymyxin B already bound to LPS. The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either i |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS584369 |
Price | $610 |
Order / More Info | Polymyxin B (PMB) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Appelmelk, B et al; Polymyxin B-horseradish peroxidase conjugates as tools in endotoxin research. Anal Biochem 1992, 207: 311 |