Polymyxin B (PMB) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPolymyxin B (PMB)
Clone[45]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM
Formatunconjugated
Size0.2 mg
Concentrationn/a
ApplicationsImmunoassay (IA), Western Blot (WB)
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DescriptionProduct Description: The monoclonal antibody 45 reacts with Polymyxin B. The antibody binds to free Polymyxin B as well as to Polymyxin B already bound to LPS. The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either i
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS584369
Price$610
Order / More InfoPolymyxin B (PMB) Antibody from MYBIOSOURCE INC.
Product Specific References1. Appelmelk, B et al; Polymyxin B-horseradish peroxidase conjugates as tools in endotoxin research. Anal Biochem 1992, 207: 311
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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