Phospho-SMYD2 (Ser283) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-SMYD2 (Ser283) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phospho-SMYD2 (Ser283) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: porcine, bovine, horse, rabbit, dog, chicken |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-SMYD2(Ser283) Antibody detects endogenous levels of SMYD2 only when phosphorylated at Ser283. Description: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.Subunit Structure: Interacts with RNA polymerase II and HELZ. Interacts with SIN3A and HDAC1 (By similarity). Interacts (via MYND-type zinc finger) with EPB41L3 |
| Immunogen | Immunogen: A synthesized peptide derived from human SMYD2 around the phosphorylation site of Ser283. Tissue Specificity: Expression is repressed by CEBPA. |
| Other Names | [Histone methyltransferase SMYD2; HSKM B; HSKM-B; HSKMB; KMT3C; Lysine N-methyltransferase 3C; MGC119305; N lysine methyltransferase SMYD2; N-lysine methyltransferase SMYD2; SET and MYND domain containing 2; SET and MYND domain containing protein 2; SET and MYND domain-containing protein 2; Smyd2; SMYD2_HUMAN; Zinc finger MYND domain containing 14; ZMYND14] |
| Gene, Accession # | [SMYD2], Gene ID: 56950, NCBI: Q9NRG4.2, UniProt: Q9NRG4 |
| Catalog # | MBS9610453 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-SMYD2 (Ser283) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies