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Antigenic Specificity | CHAT/Choline Acetyltransferase Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been |
Immunogen | Immunogen: E Coli-derived human CHAT recombinant protein (Position: D446-R652). Human CHAT shares 88.4% and 87% amino acid (aa) sequence identity with mouse and rat CHAT, respectively. |
Other Names | [Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase; 2.3.1.6; CHAT] |
Gene, Accession # | [CHAT], Gene ID: 1103, NCBI: NP_001136401.1, UniProt: P28329 |
Catalog # | MBS1750590 |
Price | $315 |
Order / More Info | CHAT/Choline Acetyltransferase Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |