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Antigenic Specificity | Phospho-STAT1 (Ser727) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-STAT1 (Ser727) antibody detects endogenous levels of STAT1 only when phosphorylated at Serine 727. Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators.Function: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activati |
Immunogen | Immunogen: A synthesized peptide derived from human STAT1 around the phosphorylation site of Serine 727 Subcellular Location: Cytoplasm. Nucleus. Translocated into the nucleus in response to IFN-gamma-induced tyrosine phosphorylation and dimerization. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (91%), Dog (100%), Chicken (91%), Xenopus (89%) |
Other Names | [CANDF7; DKFZp686B04100; ISGF 3; ISGF3; OTTHUMP00000163552; OTTHUMP00000165046; OTTHUMP00000165047; OTTHUMP00000205845; Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription 1-alpha/beta; Stat1; STAT1_HUMAN; STAT91; Transcription factor ISGF-3 components p91/p84] |
Gene, Accession # | [STAT1], Gene ID: 6772, NCBI: NP_009330.1, UniProt: P42224 |
Catalog # | MBS9601068 |
Price | $240, $280 |
Order / More Info | Phospho-STAT1 (Ser727) Antibody from MYBIOSOURCE INC. |
Product Specific References | Wu M, Chen M, Jing Y, Gu J, Mei S, Yao Q, Zhou J, Yang M, Sun L, Wang W, Hu H, Wuthrich RP, Mei C; Journal: Am J Physiol Renal Physiol. The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1. |