Alpha Synuclein Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Alpha Synuclein |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~14.46kda. Highly expressed in brain (presynaptic nerve terminals) but is also expressed in low concentrations in all tissues examined except in liver. Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the majo |
| Immunogen | Immunogen: Synthetic peptide from the full length of Human Alpha Synuclein Immunogen Species: Human |
| Other Names | [Rabbit Human Alpha Synuclein; Alpha Synuclein; Non-A4 component of amyloid precursor; MGC105443; OTTHUMP00000218552; MGC110988; OTTHUMP00000218553; Synuclein alpha 140; alphaSYN; Parkinson disease familial 1; OTTHUMP00000218554; Parkinson disease (autosomal dominant; Lewy body) 4; Synuclein; alpha (non A4 component of amyloid precursor); OTTHUMP00000218549; Non A4 component of amyloid precursor; MGC127560; SYN; SNCA; MGC64356; Non A4 component of amyloid; PARK4; Alpha synuclein; PARK 1; Snca synuclein; Synuclein alpha; Non-A4 component of amyloid; precursor of; OTTHUMP00000218551; PARK 4; PARK1; Alpha-synuclein; isoform NACP140; Non-A-beta component of alzheimers disease amyloid; Non-A beta component of AD amyloid; NACP; SYUA_HUMAN; Alpha-synuclein; Non A beta component of AD amyloid] |
| Gene, Accession # | Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840 |
| Catalog # | MBS8002048 |
| Price | $390 |
| Order / More Info | Alpha Synuclein Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Genetics Home Reference: SNCA. US National Library of Medicine. (2013). 2. Zhang L., et al. (2008) Brain Res. 1244: 40-52. 3. Alim M.A., et al. (2002) J Biol Chem. 277(3): 2112-2117. 4. Kokhan V.S., Afanasyeva M.A., Van'kin G. (2012) Behav. Brain. Res. 231(1): 226-230. 5. Spillantini M.G., et al. (1997) Nature. 388(6645): 839-840. 6. Mezey E., et al. (1998) Nat Med. 4(7): 755-757. |
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