Edit |   |
---|---|
Antigenic Specificity | MEKK6 (C-term), 1028-1058 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.11 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6. Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 6; Apoptosis signal-regulating kinase 2; MAP3K6; ASK2; MAPKKK6; MEKK6] |
Gene, Accession # | [MAP3K6], Gene ID: 9064, NCBI: NP_004663.3, UniProt: O95382 |
Catalog # | MBS9205448 |
Price | $165, $370 |
Order / More Info | MEKK6 (C-term), 1028-1058 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang, X.S., et al., Biochem. Biophys. Res. Commun. 253(1):33-37 (1998). |