Cathepsin D Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCathepsin D
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe purified antibody detects both the 52 kDa proform and the 34 kDa cleaved fragment of Cathepsin D. Background: Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro-enzyme. Activation involves the proteolytic removal of the 43 amino acid profragment and an internal cleavage to generate the two-chain form made up of 34 and 14 kDa subunits. Cathepsin D contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. In certain tumor cells, Cathepsin D
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 140 of mouse cathepsin D
Other Names[CTSD; CLN10; CPSD; MGC2311], [CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD]
Gene, Accession #Gene ID: 1509, NCBI: NP_001900.1
Catalog #MBS840224
Price$150, $300
Order / More InfoCathepsin D Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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