MYSM1 (N-term), 111-139 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MYSM1 (N-term), 111-139 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MYSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
| Immunogen | n/a |
| Other Names | [Histone H2A deubiquitinase MYSM1; 2A-DUB; 3419-; Myb-like; SWIRM and MPN domain-containing protein 1; MYSM1; KIAA1915] |
| Gene, Accession # | [MYSM1], Gene ID: 114803, NCBI: NP_001078956.1, UniProt: Q5VVJ2 |
| Catalog # | MBS9207773 |
| Price | $165, $370 |
| Order / More Info | MYSM1 (N-term), 111-139 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dephoure, N., et al. Proc. Natl. Acad. Sci. U.S.A. 105(31):10762-10767(2008) Zhu, P., et al. Mol. Cell 27(4):609-621(2007) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Yoneyama, M., et al. J. Mol. Biol. 369(1):222-238(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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