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Antigenic Specificity | TNFRSF10A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
Immunogen | Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 10A protein (263-468AA) |
Other Names | [Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261; TNFRSF10A; APO2; DR4; TRAILR1] |
Gene, Accession # | [TNFRSF10A], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220 |
Catalog # | MBS7103861 |
Price | $160, $235 |
Order / More Info | TNFRSF10A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |