TEAD3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTEAD3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total TEAD3 protein. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human ch
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TEAD3.
Other Names[Transcriptional enhancer factor TEF-5; TEA domain family member 3; TEAD-3; DTEF-1; TEAD3]
Gene, Accession #[TEAD3], Gene ID: 7005, NCBI: NP_003205.2, UniProt: Q99594
Catalog #MBS9408235
Price$200, $255
Order / More InfoTEAD3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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