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Antigenic Specificity | Human Caspase-2 |
Clone | [P1C10AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Caspase-2 is a protein which belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases has a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of Caspase-2 is induced by a variety of apoptotic stimuli. |
Immunogen | Immunogen: Anti-human Caspase-2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Caspase-2 amino acids 32-169 purified from E Coli. |
Other Names | [CASP2; Caspase-2, Mouse Human; Caspase-2; CASP-2; Protease ICH-1 Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; CASP2; ICH1; NEDD2; ICH-1L; ICH-1L/1S], [CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2; NEDD-2] |
Gene, Accession # | [CASP2], Gene ID: 835, NCBI: NP_001215.1 |
Catalog # | MBS140223 |
Price | $140, $205, $505 |
Order / More Info | Human Caspase-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |