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Antigenic Specificity | Human HTR1B / 5-HT2B Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, chimpanzee, gorilla, human, monkey, orangutan. predicted reactivity: bat, bovine (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human 5HT2B Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins. 5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood; mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation. |
Immunogen | Immunogen Description: Synthetic 15 amino acid peptide from 2nd extracellular domain of human 5HT2B Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Bovine, Bat (93%); Mouse, Hamster. |
Other Names | [HTR1B / 5-HT2B Receptor (Extracellular Domain) IHC-plus; HTR2B; 5-HT 2B receptor; 5HT2B Receptor; 5-HT(2B); 5-HT-2B; 5-HT2b receptor; 5-HT2B; Serotonin 2b receptor; Serotonin 5-HT-2b receptor; Serotonin receptor 2B; Human HTR1B; 5-HT2B Receptor], [HTR2B] |
Gene, Accession # | [HTR1B], Gene ID: 3357, NCBI: NP_000858.3, UniProt: P41595 |
Catalog # | MBS243367 |
Price | $530 |
Order / More Info | Human HTR1B / 5-HT2B Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |