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Antigenic Specificity | Phospho-PKC alpha (Tyr365) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PKC alpha (Tyr365) Antibody detects endogenous levels of PKC alpha only when phosphorylated at Tyr365. Description: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating |
Immunogen | Immunogen: A synthesized peptide derived from human PKC alpha around the phosphorylation site of Tyr365. |
Other Names | [AAG6; Aging associated gene 6; aPKC; KPCA_HUMAN; PKC alpha; PKC-alpha; PKCA; PRKACA; PRKCA; Protein Kinase C alpha; Protein kinase C alpha type] |
Gene, Accession # | [PKC-A], Gene ID: 5578, NCBI: NP_002728.1, UniProt: P17252 |
Catalog # | MBS9610601 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PKC alpha (Tyr365) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |