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Antigenic Specificity | RHEB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rheb (Ras Homolog Enriched in Brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure (1). While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Like other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway (2). Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/TOR signaling pathway (3-6). The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of n |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [RHEB; MGC111559; RHEB2], [RHEB; RHEB; RHEB2; RHEB2] |
Gene, Accession # | [RHEB], Gene ID: 6009, NCBI: Q15382.1, UniProt: Q15382 |
Catalog # | MBS128069 |
Price | $200, $275, $430 |
Order / More Info | RHEB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |