Edit |   |
---|---|
Antigenic Specificity | CBX7 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CBX7. It was validated on Western BlotTarget Description: CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by ind |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7 |
Other Names | [chromobox protein homolog 7 isoform 1; Chromobox protein homolog 7; chromobox protein homolog 7; chromobox 7] |
Gene, Accession # | [CBX7], Gene ID: 23492, NCBI: NP_783640.1, UniProt: O95931 |
Catalog # | MBS3219683 |
Price | $335 |
Order / More Info | CBX7 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |