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Antigenic Specificity | KDM2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: porcine, bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KDM2B Antibody detects endogenous levels of KDM2B. Description: Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Subunit Structure: Directly interacts with SKP1 and CUL1.Similarity: The JmjC domain m |
Immunogen | Immunogen: A synthesized peptide derived from human KDM2B. |
Other Names | [[Histone-H3]-lysine-36 demethylase 1B; CXXC-type zinc finger protein 2; CXXC2; F box and leucine rich repeat protein 10; F box protein FBL10; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; Fbl10; FBXL10; JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein; JHDM1B; JmjC domain-containing histone demethylation protein 1B; Jumonji C domain containing histone demethylase 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; kdm2b; KDM2B_HUMAN; Lysine (K) specific demethylase 2B; Lysine-specific demethylase 2B; PCCX2; Protein containing CXXC domain 2; Protein JEMMA; Protein-containing CXXC domain 2] |
Gene, Accession # | [KDM2B], Gene ID: 84678, NCBI: NP_001005366.1, UniProt: Q8NHM5 |
Catalog # | MBS9611302 |
Price | $240, $280 |
Order / More Info | KDM2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |