EGFR (Ser-967), phospho-specific Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | EGFR (Ser-967), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to unphosphorylated EGFR (Ser-967) coupled to agarose then affinity purified using phospho- EGFR (Ser-967) peptide (without carrier). The antibody detects a 180 kDa* protein on SDS-PAGE immunoblots of human A431 cells treated with Calyculin A, and does not detect this band after lambda phosphatase treatment. The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with an extracellular ligand-binding domain and a cytoplasmic domain with intrinsic tyrosine kinase activity. The cytoplasmic domain has a C-terminal region with multiple autophosphorylation sites (Tyr-992, 1068, 1086, 1148, and 1173). These sites are important for downstream signaling and rapid internalization. In addition, EGFR |
| Immunogen | Immunogen: Phospho-EGFR (Ser-967) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 967 of human EGFR (ErbB-1). This human EGFR sequence has high homology to rat and mouse EGFR, and low homology to other ErbB family members. |
| Other Names | [Epidermal Growth Factor Receptor; ErbB-1], [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1] |
| Gene, Accession # | Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
| Catalog # | MBS472024 |
| Price | $385 |
| Order / More Info | EGFR (Ser-967), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Carpenter, G. (2000) Bioessays 22:697.• Boeri Erba, E. et al. (2005) Mol. Cell. Prot. 4:1107. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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