Edit |   |
---|---|
Antigenic Specificity | SLC1A7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist. The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4) |
Immunogen | Immunogen: SLC1A7 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLC1A7. Buffer: SLC1A7 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Solute carrier family 1 (glutamate transporter) member 7; AAAT; excitatory amino acid transporter 5; EAAT5; solute carrier family 1 (glutamate transporter), member 7], [SLC1A7; SLC1A7; AAAT; EAAT5; EAAT5] |
Gene, Accession # | [SLC1A7], Gene ID: 6512, NCBI: NP_001274524, UniProt: O00341 |
Catalog # | MBS153404 |
Price | $375 |
Order / More Info | SLC1A7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |