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Antigenic Specificity | Human CD23 |
Clone | [4AEBVCS2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 tests, 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 4AEBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelets. Expression of CD23 is upregulatedupon B cell activation, and soluble forms of the antigen have been reported to be biologically active. CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B cell activation. CD21 and the alpha subunit of CD11b and CD11c bind to CD23. |
Immunogen | n/a |
Other Names | [CD23; CD23 protein; low affinity immunoglobulin epsilon Fc receptor; Fc fragment of IgE receptor II; CD23 protein] |
Gene, Accession # | [CD23], Gene ID: 171075, NCBI: CAA51981.1, UniProt: Q63097 |
Catalog # | MBS8500637 |
Price | $280, $350 |
Order / More Info | Human CD23 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. 2.McMichael, A.J., P.C.L. Beverly, et al. eds. (1987). Leucocyte Typing III: White Cell Differentiation Antigens. Oxford University Press. New York. 3.Bernard, A., et al. eds. (1981). Leukocyte Typing. Springer-Verlag. |