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Antigenic Specificity | Human Rho guanine nucleotide exchange factor 7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding prote |
Immunogen | Immunogen: Recombinant human Rho guanine nucleotide exchange factor 7 protein |
Other Names | [Beta-Pix; COOL-1; PAK-interacting exchange factor beta; p85; ARHGEF7; COOL1; KIAA0142; P85SPR; PAK3BP; PIXB ORF Names: Nbla10314] |
Gene, Accession # | Gene ID: 8874, NCBI: NP_001106983.1, UniProt: Q14155 |
Catalog # | MBS7006832 |
Price | $160, $235 |
Order / More Info | Human Rho guanine nucleotide exchange factor 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |