Human Rho guanine nucleotide exchange factor 7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Rho guanine nucleotide exchange factor 7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionActs as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding prote
ImmunogenImmunogen: Recombinant human Rho guanine nucleotide exchange factor 7 protein
Other Names[Beta-Pix; COOL-1; PAK-interacting exchange factor beta; p85; ARHGEF7; COOL1; KIAA0142; P85SPR; PAK3BP; PIXB ORF Names: Nbla10314]
Gene, Accession #Gene ID: 8874, NCBI: NP_001106983.1, UniProt: Q14155
Catalog #MBS7006832
Price$160, $235
Order / More InfoHuman Rho guanine nucleotide exchange factor 7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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