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Antigenic Specificity | PGRMC1 |
Clone | [1C10D11] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Progesterone receptor membrane component 1 (PGRMC1) is a member of a multi-protein progesterone-binding complex. However, PGRMC1 shares homology with cytochrome b5-related proteins rather than hormone receptors. It is a heme binding protein with biding sites for Src homology (SH2) and SH3 domain-containing proteins. PGRMC1 is overexpressed in a variety of cancers, and thus represents an important biomarker for cancer progression and a potential target for anticancer drugs. In nonmalignant tissues, PGRMC1 is highly expressed in the liver and kidney. |
Immunogen | Immunogen: Fusion protein of PGRMC1 |
Other Names | [HPR6.6; Membrane associated progesterone receptor component 1; Membrane-associated progesterone receptor component 1; mPR; PGRC1; PGRMC; Pgrmc1; Progesterone binding protein; Progesterone receptor membrane component 1] |
Gene, Accession # | [PGRMC1], Gene ID: 10857, NCBI: NP_001269550.1, UniProt: O00264 |
Catalog # | MBS2527508 |
Price | $220, $290, $435 |
Order / More Info | PGRMC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |