Edit |   |
---|---|
Antigenic Specificity | GAD65 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 353 and 556 of GAD65 |
Other Names | [Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase 2; glutamate decarboxylase 2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform] |
Gene, Accession # | [GAD65], Gene ID: 2572, NCBI: AAI26328 |
Catalog # | MBS9404146 |
Price | $320 |
Order / More Info | GAD65 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |