Edit |   |
---|---|
Antigenic Specificity | Phospho-MAPKAPK5(Thr182) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MAPKAPK5(Thr182) antibody detects endogenous levels of MAPKAPK5 only when phosphorylated at Threonine 182. Description: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.Function: Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Ph |
Immunogen | Immunogen: A synthesized peptide derived from human MAPKAPK5 around the phosphorylation site of Threonine 182 Subcellular Location: Cytoplasm. Nucleus. Also observed in the nucleus. Tissue Specificity: Expressed ubiquitously. |
Other Names | [MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPK5_HUMAN; MAPKAP kinase 5; MAPKAPK-5; MAPKAPK5; Mitogen activated protein kinase activated protein kinase 5; p38-regulated/activated protein kinase; PRAK] |
Gene, Accession # | [MAPKAPK5], Gene ID: 8550, NCBI: NP_003659.2, UniProt: Q8IW41 |
Catalog # | MBS9600028 |
Price | $240, $280 |
Order / More Info | Phospho-MAPKAPK5(Thr182) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |