Phospho-MAPKAPK5(Thr182) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAPKAPK5(Thr182)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-MAPKAPK5(Thr182) antibody detects endogenous levels of MAPKAPK5 only when phosphorylated at Threonine 182. Description: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.Function: Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Ph
ImmunogenImmunogen: A synthesized peptide derived from human MAPKAPK5 around the phosphorylation site of Threonine 182 Subcellular Location: Cytoplasm. Nucleus. Also observed in the nucleus. Tissue Specificity: Expressed ubiquitously.
Other Names[MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPK5_HUMAN; MAPKAP kinase 5; MAPKAPK-5; MAPKAPK5; Mitogen activated protein kinase activated protein kinase 5; p38-regulated/activated protein kinase; PRAK]
Gene, Accession #[MAPKAPK5], Gene ID: 8550, NCBI: NP_003659.2, UniProt: Q8IW41
Catalog #MBS9600028
Price$240, $280
Order / More InfoPhospho-MAPKAPK5(Thr182) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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