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Antigenic Specificity | Integrin beta3 (Ab-773) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Integrin b3 protein. Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa. 771~775 (P-L-Y-K-E) derived from Human Integrin b3. |
Other Names | [Integrin b3 (Ab-773); Platelet membrane glycoprotein IIIa] |
Gene, Accession # | Gene ID: 3690, NCBI: NP_000203.2, UniProt: P05106 |
Catalog # | MBS9401268 |
Price | $200, $255 |
Order / More Info | Integrin beta3 (Ab-773) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |