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Antigenic Specificity | Cathepsin B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Cathepsin B(CTSB) detection. Tested with WB in Human. Background: Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. And this gene is mapped to chromosome 8p22. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 |
Immunogen | Immunogen: E Coli-derived human Cathepsin B recombinant protein (Position: L80-D333). Human Cathepsin B shares 83% and 84% amino acid (aa) sequences identity with mouse and rat Cathepsin B, respectively. |
Other Names | [Cathepsin B; cathepsin B; Amyloid precursor protein secretase; APP secretase; APPS; CATB_HUMAN; Cathepsin B; Cathepsin B heavy chain; Cathepsin B1; CathepsinB; CPSB; CTSB; Cysteine protease; OTTHUMP00000116009; OTTHUMP00000229510; OTTHUMP00000229511; OTTHUMP00000229512; OTTHUMP00000229514; OTTHUMP00000229515; OTTHUMP00000229516; Preprocathepsin B], [CTSB; CTSB; APPS; CPSB; CPSB; APPS] |
Gene, Accession # | [CTSB], Gene ID: 1508, NCBI: P07858.3, UniProt: P07858 |
Catalog # | MBS176815 |
Price | $280 |
Order / More Info | Cathepsin B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |