BIM/BOD (IN) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BIM/BOD (IN) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.025 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~23kDa. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously exp |
| Immunogen | Immunogen: Internal central amino acids of human Bim Immunogen Species: Human |
| Other Names | [Rabbit Human BIM/BOD (IN); BCL2 like protein 11; Bcl2 interacting mediator of cell death; Bcl2 interacting protein Bim; BCL2 like 11; BAM; BimEl; BimL; BOD; BIM beta 6; BIM Beta7; BIM alpha 3; BIM alpha4; BIM alpha5; BIM alpha6] |
| Gene, Accession # | [BIM/BOD], Gene ID: 10018, NCBI: NP_001191035.1, UniProt: O43521 |
| Catalog # | MBS8001992 |
| Price | $215 |
| Order / More Info | BIM/BOD (IN) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. O'Connor L., Strasser A., O'Reilly L.A., et al. (1998) EMBO J. 17: 384-395. 2. Hsu S.Y., Lin P., and Hsueh A.J. (1998) Mol. Endocrinol. 12: 1432-40. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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