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Antigenic Specificity | TPM3 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1,k |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TPM3 antibody is generated from a mouse immunized with a recombinant protein of human TPM3. Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
Immunogen | n/a |
Other Names | [Tropomyosin alpha-3 chain; Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5; TPM3] |
Gene, Accession # | [TPM3], Gene ID: 7170, NCBI: NP_001036816.1, UniProt: P06753 |
Catalog # | MBS9217033 |
Price | $165, $370 |
Order / More Info | TPM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Reinach F.C.,et al.Nature 322:648-650 (1986). McLeod A.R.,et al.Nucleic Acids Res. 14:8413-8426 (1986). Clayton L.,et al.J. Mol. Biol. 201:507-515 (1988). Lin J.J.-C.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. Gregory S.G.,et al.Nature 441:315-321 (2006). |