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Antigenic Specificity | FZD10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differen |
Immunogen | Immunogen: Recombinant Human Frizzled-10 protein (125-225AA) |
Other Names | [Frizzled-10; Fz-10; hFz10; FzE7; CD_antigen: CD350; FZD10] |
Gene, Accession # | [FZD10], Gene ID: 11211, NCBI: NP_009128.1, UniProt: Q9ULW2 |
Catalog # | MBS7105465 |
Price | $160, $235 |
Order / More Info | FZD10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |