CCAR2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CCAR2 |
| Clone | [3G4-D11-D7] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti CCAR2 antibody recognizes cell cycle and apoptosis regulator protein 2 (CCAR2), also known as DBC1 and KIAA1967. The Dbc1 gene was discovered to be homozygously deleted in human chromosome 8p21 in breast cancer (Hamaguchi et al. 2002). CCAR2 regulates ER beta function (Koyama et al. 2010), heterochromatin formation (Li et al. 2009) and negatively regulates the NAD-dependent protein deacetylase sirtuin-1 (SIRT1) (Kim et al. 2008). In addition, DBC1 has also been shown to act as a tumor suppressor by regulating p53 binding; CCAR2 competes with MDM2 for binding to p53 (Qin et al. 2015). |
| Immunogen | Immunogen: Recombinant human CCAR2 protein fragments expressed in E Coli. |
| Other Names | [CCAR2 (3G4-D11-D7)], [CCAR2; KIAA1967; DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967; DBC1; DBC-1; DBC.1] |
| Gene, Accession # | [CCAR2], Gene ID: 57805, NCBI: NP_066997.3, UniProt: Q8N163 |
| Catalog # | MBS225708 |
| Price | $405 |
| Order / More Info | CCAR2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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