Thrombomodulin/CD141 (Endothelial Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityThrombomodulin/CD141 (Endothelial Cell Marker)
Clone[THBD/1591]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposis sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
ImmunogenImmunogen: Recombinant human Thrombomodulin protein fragment (aa69-194) Cellular Localization: Cell Surface & Cytoplasmic
Other Names[AHUS6; BDCA3; CD141; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin (TM)]
Gene, Accession #[THBD], Gene ID: 7056, NCBI: NP_000352.1, UniProt: P07204
Catalog #MBS4380250
Price$190, $340, $340
Order / More InfoThrombomodulin/CD141 (Endothelial Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAppleton MA, Attanoos RL, Jasani B. Thrombomodulin as a marker of vascular and lymphatic tumours. Histopathology. 1996 Aug; 29(2):153-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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