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Antigenic Specificity | Mouse CD18 |
Clone | [M12/2] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD18 is a 95 kD protein, also known as integrin beta2 subunit. It is expressed on all leukocytes. CD18, in association with integrin alpha chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and alphaXbeta2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion. |
Immunogen | n/a |
Other Names | [Mouse CD18; Integrin beta-2; Itgb2; Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta; Complement receptor C3 subunit beta; CD18] |
Gene, Accession # | [CD18], Gene ID: 16414, NCBI: NP_032430.2, UniProt: P11835 |
Catalog # | MBS2553975 |
Price | $75, $90 |
Order / More Info | Mouse CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175. 3. Wilson RW, et al. 1993. J. Immunol. 151:1571. |