MKK7 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | MKK7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human MKK7. MKK7 is a MAP kinase kinase that serves as a specific activator of JNK/SAPK pathway (1,2). MKK7 is activated strongly by TNFalpha, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and JNK/SAPK pathways, is not activated by TNFalpha (2). Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity. |
| Immunogen | Immunogen: A synthetic -peptide of human MKK7 |
| Other Names | [MAP2K7; MAP2K7, Jnkk2, MAPKK7, MKK7, PRKMK7, Dual specificity mitogen-activated protein kinase kinase 7, c-Jun N-terminal kinase kinase 2], [MAP2K7; MAP2K7; MKK7; Jnkk2; MAPKK7; PRKMK7; SAPKK4; SAPKK-4; JNKK2; MEK7; MKK7; PRKMK7; SKK4; MAP kinase kinase 7; MAPKK 7; MEK 7; SAPK kinase 4; SAPKK-4; SAPKK4; JNK kinase 2; JNKK 2] |
| Gene, Accession # | Gene ID: 5609, NCBI: NP_660186.1, UniProt: O14733 |
| Catalog # | MBS126072 |
| Price | $275, $430 |
| Order / More Info | MKK7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Tournier, C. et al. (1999) Mol. Cell. Biol. 19, 1569-1581. 2. Moriguchi, T. et al. (1997) EMBO J. 16, 7045-7053. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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