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Antigenic Specificity | mGluR7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: mGluR7 antibody detects endogenous levels of total mGluR7. Description: mGluR7 Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. Interacts with PICK1. 5 isoforms of the human protein are produced by alternative splicing.Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Subunit Structure: Interacts with PICK1.Similarity: Belongs to the G-protein coup |
Immunogen | Immunogen: A synthesized peptide derived from human mGluR7 Subcellular Location: Cell Membrane Tissue Specificity: Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. Predicted Cross Reactivity: Bovine, Horse, Dog Similarity: Bovine (100%), Horse (100%), Dog (100%) |
Other Names | [FLJ40498; GLUR7; Glutamate receptor metabotropic 7; GPRC1G; GRM7; GRM7_HUMAN; Metabotropic glutamate receptor 7; MGLU7; mGluR7; OTTHUMP00000206961; OTTHUMP00000214674; OTTHUMP00000214675] |
Gene, Accession # | [mGluR7], Gene ID: 2917, NCBI: NP_000835.1, UniProt: Q14831 |
Catalog # | MBS9600109 |
Price | $240, $280 |
Order / More Info | mGluR7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |