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Antigenic Specificity | HDAC6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation. |
Immunogen | Immunogen: Synthetic peptide mapping to the N-terminus of mouse HDAC-6 |
Other Names | [HD6; HDAC-6; histone deacetylase 6; JM21], [Hdac6; Hdac6; Hd6; Sfc6; Hdac5; mHDA2; HD6] |
Gene, Accession # | [HDAC6], Gene ID: 15185, NCBI: NP_001123888.1, UniProt: Q9Z2V5 |
Catalog # | MBS841120 |
Price | $150, $330 |
Order / More Info | HDAC6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |