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Antigenic Specificity | Human CD137L (4-1BB Ligand) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Antibody ANC5D6 binds to CD137L present on Raji and U-937 cells, and also binds to recombinant CD137L-muCD8 in EIA and Western Blot. mAb name/Clone: ANC5D6Human CD137 Ligand is a type II transmembrane protein constitutively expressed by monocytes, B cells neuroblastoma cells (1), and some activated T cells. The interaction of CD137 (4-1BB) and CD137L can supply a costimulatory signal to T cells through CD137. This costimulus seems to be more effective for CD8+ effector T cells than for CD4+ helper T cells (3). The interaction can also effect a reverse signal, inducing monocyte activation (2), or T cell inactivation and programmed death (4) through CD137L. |
Immunogen | Immunogen: Recombinant human CD137L |
Other Names | n/a |
Gene, Accession # | [CD137L] |
Catalog # | MBS4159597 |
Price | $540 |
Order / More Info | Human CD137L (4-1BB Ligand) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |