Edit |   |
---|---|
Antigenic Specificity | Human Heparanase-1 3/17 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | purified |
Size | 0.05 mg, 0.1 mg, 0.15 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HP3/17 reacts with the 50 kDa subunit and with the 65 kDa precursor of human or mouse Heparanase by Western blotting and immunohistochemistry. Recommended dilution range for Western blot analysis: 1:4000. Recommended dilution range for immunohistochemistry: 1:40. Heparanase is an endo-beta-D-glucuronidase, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix. Heparanase plays an important role in ECM degradation, facilitating the migration and extravasation of tumor cells and inflammatory leukocytes (1,2,3). Upon degradation, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis (4,5). Heparanase is a heterodimer comprised of |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [HEP-1 3/17] |
Catalog # | MBS140055 |
Price | $360, $490, $645 |
Order / More Info | Human Heparanase-1 3/17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |