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Antigenic Specificity | NFATC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The NFAT (nuclear factor of activated T cells) family of proteins consists of NFAT1 (NFATc2 or NFATp), NFAT2 (NFATc1 or NFATc), NFAT3 (NFATc4), and NFAT4 (NFATc3 or NFATx). All members of this family are transcription factors with a Rel homology domain and regulate gene transcription in concert with AP-1 (Jun/Fos) to orchestrate an effective immune response (1,2). NFAT proteins are predominantly expressed in cells of the immune system, but are also expressed in skeletal muscle, keratinocytes, and adipocytes, regulating cell differentiation programs in these cells (3). In resting cells, NFAT proteins are heavily phosphorylated and localized in the cytoplasm. Increased intracellular calcium concentrations activate the calcium/calmodulin-depen |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human NFATC1 (NP 765978.1). Calculated MW: 38 kDa/74kDa-88kDa/100-101kDa Observed MW: 80kDa Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [NFATC1; NF-ATC; NF-ATc1.2; NFAT2; NFATc; nuclear factor of activated T-cells 1], [NFATC1; NFATC1; NFAT2; NFATc; NF-ATC; NFAT2; NFATC; NF-ATc1; NFATc1; NF-ATc; NFATc] |
Gene, Accession # | [NFATC1], Gene ID: 4772, NCBI: O95644.3, UniProt: O95644 |
Catalog # | MBS127656 |
Price | $200, $275, $430 |
Order / More Info | NFATC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |