Edit |   |
---|---|
Antigenic Specificity | Human VEGFR-1/Flt-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant human soluble Vascular Endothelial Growth Factor Receptor-1 (sVEGFR-1) is the naturally occurring form and was cloned from total RNA of human umbilical vein endothelial cells.The recombinant mature sVEGFR-1 is a glycosylated monomeric protein with a mass of approximately 96kDa. The soluble receptor protein consists of the first 6 extracellular domains (Met1-His688) containing the unique 31 amino acids residues at the C-terminus. Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), and VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, bu |
Immunogen | Immunogen: Recombinant human soluble Flt-1(D1-5). Cross Reactivity: Not Determined |
Other Names | [Fms-like tyrosine kinase 1, Vascular permeability factor receptor], [FLT1; FLT1; FLT; FLT-1; VEGFR1; VEGFR-1; FLT; FRT; VEGFR1; VEGFR-1; FLT-1; FLT] |
Gene, Accession # | [VEGFR-1/Flt-1], Gene ID: 2321, NCBI: NP_001153392, UniProt: P17948.2 |
Catalog # | MBS691217 |
Price | $340 |
Order / More Info | Human VEGFR-1/Flt-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barleon et al., 1997, J Biol Chem 272:10382-8 2. Rockl et al., 1998, Exp Cell Res, 241: 161-170]. |