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Antigenic Specificity | IDE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using IDE antibody. Immunohistochemistry of paraffin-embedded human stomach cancer using IDE antibody at dilution of 1:200 (400x lens). This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in thi |
Immunogen | Immunogen: Recombinant protein of human IDE |
Other Names | n/a |
Gene, Accession # | [IDE] |
Catalog # | MBS419738 |
Price | $385 |
Order / More Info | IDE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |