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Antigenic Specificity | Catenin, delta-1 (CTNND1) (pTyr96) |
Clone | [25a] |
Host Species | Mouse |
Reactive Species | human, rat. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The membrane associated protein pp120 Src substrate (p120 Catenin, p120cas) was identified as a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. It shares structural similarity with the Drosophila Armadillo protein and the vertebrate beta-catenin and gamma-catenin proteins. Its characteristic Arm domain that is composed of 42-amino acid motif repeats evidences this similarity. In the cell, p120 Catenin is localized to the E-Cadherin/catenins cell adhesion complex. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other Cadherins. It exists as four isoforms that ra |
Immunogen | Immunogen: Mouse p120 Catenin (pY96). Cellular Localization: Cell Surface |
Other Names | [Cadherin-associated Src substrate (CAS); Catenin (cadherin associated protein) delta 1; Catenin delta-1; CTNND1; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN], [CTNND1; KIAA0384; CAS; p120(ctn)] |
Gene, Accession # | [CTNND1], Gene ID: 1500, NCBI: NP_001078927.1, UniProt: O60716 |
Catalog # | MBS439904 |
Price | $190, $340, $340 |
Order / More Info | Catenin, delta-1 (CTNND1) (pTyr96) Antibody from MYBIOSOURCE INC. |
Product Specific References | Reynolds, Daniel, McCrea et al.: Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8333-42, 1994. Mariner, Anastasiadis, Keilhack et al.: Identification of Src phosphorylation sites in the catenin p120ctn. in: The Journal of biological chemistry, Vol. 276, Issue 30, pp. 28006-13, 2001 |