HSPC142 (N-term), 9-37 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HSPC142 (N-term), 9-37 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, zebrafish) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This HSPC142 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human HSPC142. HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. HSPC142 probably also plays a role as a component of the BRISC complex, a multiprotein co |
| Immunogen | n/a |
| Other Names | [BRISC and BRCA1-A complex member 1; Mediator of RAP80 interactions and targeting subunit of 40 kDa; New component of the BRCA1-A complex; BABAM1; C19orf62; MERIT40; NBA1] |
| Gene, Accession # | [BABAM1], Gene ID: 29086, NCBI: NP_001028721.1, UniProt: Q9NWV8 |
| Catalog # | MBS9203696 |
| Price | $165, $370 |
| Order / More Info | HSPC142 (N-term), 9-37 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Solyom, S., et al. Breast Cancer Res. Treat. 120(1):165-168(2010) Cooper, E.M., et al. EMBO J. 28(6):621-631(2009) Olsen, J.V., et al. Cell 127(3):635-648(2006) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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