Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC.

Search, find, compare suppliers for anti-Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) antibody, protein, ELISA kits.

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Antigenic SpecificityGlypican-3 (GPC3) (Hepatocellular Carcinoma Marker)
Clone[SPM595]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatCF555 conjugate
Size0.5 mL
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
ImmunogenImmunogen: A recombinant fragment containing amino acids 511-580 of human glypican-3
Other Names[DGSX; Glypican proteoglycan 3; GPC3; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI-5; MXR7; OCI-5; SDYS; Secreted glypican-3; SGBS1]
Gene, Accession #[GPC3], Gene ID: 2719, NCBI: NP_001158091.1, UniProt: P51654
Catalog #MBS4380943
Price$340
Order / More InfoGlypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYan, B., et al. 2011. Ann. Diagn. Pathol. 15: 162-169.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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