KIDINS220 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKIDINS220
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPromotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induc
ImmunogenImmunogen: Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA) Conjugation: Non-conjugated
Other Names[Kinase D-interacting substrate of 220 kDa; Ankyrin repeat-rich membrane-spanning protein; KIDINS220; ARMS; KIAA1250]
Gene, Accession #[KIDINS220], Gene ID: 57498, NCBI: NP_065789.1, UniProt: Q9ULH0
Catalog #MBS7052109
Price$160, $235
Order / More InfoKIDINS220 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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