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Antigenic Specificity | KIDINS220 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induc |
Immunogen | Immunogen: Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA) Conjugation: Non-conjugated |
Other Names | [Kinase D-interacting substrate of 220 kDa; Ankyrin repeat-rich membrane-spanning protein; KIDINS220; ARMS; KIAA1250] |
Gene, Accession # | [KIDINS220], Gene ID: 57498, NCBI: NP_065789.1, UniProt: Q9ULH0 |
Catalog # | MBS7052109 |
Price | $160, $235 |
Order / More Info | KIDINS220 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |