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Antigenic Specificity | VEGF Receptor 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Vascular endothelial growth factor receptor 1 (FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.Protein Function: Tyrosine-protein kinas |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human VEGF Receptor 1 (AVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLL). Subcellular Localization: Isoform 1: Cell membrane; Autophosphorylation promotes ubiquitination and endocytosis. Tissue Specificity: Detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform 2 is strongly expressed in plac |
Other Names | [Vascular endothelial growth factor receptor 1; VEGFR-1; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; FLT; Vascular permeability factor receptor; FLT1; FLT; FRT; VEGFR1] |
Gene, Accession # | [FLT1], Gene ID: 2321, NCBI: NP_001153392.1, UniProt: P17948 |
Catalog # | MBS1750430 |
Price | $280 |
Order / More Info | VEGF Receptor 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |