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Antigenic Specificity | ADRA1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [Homo sapiens adrenoceptor alpha 1B (ADRA1B), mRNA; Alpha-1B adrenergic receptor; alpha-1B adrenergic receptor; adrenergic, alpha-1B-, receptor; alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; adrenoceptor alpha 1B; Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor], [ADRA1B; ADRA1B; ADRA1; ALPHA1BAR] |
Gene, Accession # | [ADRA1B], Gene ID: 147, NCBI: NP_000670.1 |
Catalog # | MBS416182 |
Price | $230 |
Order / More Info | ADRA1B Antibody from MYBIOSOURCE INC. |
Product Specific References | (1)Staal SP, Huebner K, Croce CM et,al Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. J. Biol. Chem. 1991;266 (10): 6365-6369 |