ERAB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityERAB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsImmunohistology
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DescriptionThis antibody reacts with human. The other species are not tested. Mutations in several genes associated with early onset Alzheimer's result in increased extracellular concentrations of the longer form of the beta-amyloid peptide Ab 1-42 relative to Ab 1-40. It is this longer form of Ab that has been shown to be toxic to neurons and may serve as a catalyst for the aggregation and deposition of Ab to produce the neurotoxic effects associated with senile plaque formation. Using the Ab peptide in a yeast two-hybrid screen, a novel interacting protein designated the endoplasmic reticulum-associated amyloid betapeptide-binding protein (ERAB)/L-3-hydroxyacyl-CoA dehydrogenase type II has been identified. It is shown to be expressed at high levels
ImmunogenAntigen Preparation: A synthetic peptide corresponding to aa 100-116 of human ERAB protein.
Other Namesn/a
Gene, Accession #[ERAB]
Catalog #MBS462183
Price$270
Order / More InfoERAB Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHe, X.Y., et al., J. Biol. Chem., 273, 10741 (1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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