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Antigenic Specificity | A1CF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
Immunogen | n/a |
Other Names | [APOBEC1 complementation factor isoform 3; APOBEC1 complementation factor; APOBEC1 complementation factor; APOBEC-1 stimulating protein; apo-B RNA editing protein; apobec-1 complementation factor (ACF) (ASP); APOBEC1 complementation factor; APOBEC1-stimulating protein], [A1CF; A1CF; ACF; ASP; ACF64; ACF65; APOBEC1CF] |
Gene, Accession # | [A1CF], Gene ID: 29974, NCBI: NP_001185749.1 |
Catalog # | MBS415437 |
Price | $230 |
Order / More Info | A1CF Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Strausberg,R.L., Feingold,E.A., Grouse,L.H., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) |